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Dr Y.A. (Yael) Artzy-Randrup

Assistant Professor
Faculty of Science
Institute for Biodiversity and Ecosystem Dynamics
Photographer: Shira Hillel

Visiting address
  • Science Park 904
  • Room number: C4.167
Postal address
  • Postbus 94240
    1090 GE Amsterdam
  • Profile

    I am an Assistant Professor in Theoretical Ecology at the Department Theoretical and Computational Ecology (TCE) in the Institute for Biodiversity and Ecosystem Dynamics (IBED), and a fellow of the Institute for Advanced Study (IAS) at the University of Amsterdam, the Netherlands.

    Google Scholar profile
    Research Gate profile
     


    Areas of research

    Theoretical ecology, Evolutionary theory, Infectious diseases, Network theoryComplex systems


    I am broadly interested in questions ranging from population dynamics to evolutionary theory. My research addresses questions at the interface of ecology and evolution, where complex interactions act on multiple levels of organization and at varying time scales. In many cases drivers of biological change are difficult to trace, and they integrate in ways that are poorly understood.  One field where there is an increasing realization of the significance of interactions between ecology and evolution is in the study of infectious diseases. One area I have been studying is malaria and its parasite, P. falciparum, which presents a unique framework for extending general theories with evolutionary aspects and the inclusion of temporal processes. Here, the short time-scales at which ecological and evolutionary processes take place, in a time where we have increasing availability and richness of data from multiple scales, the growing accessibility to computational power and advanced informatics tools, and rapid evolution of powerful machine learning approaches, now make it possible to qualitatively and quantitatively address questions on ecological and evolutionary feedbacks, creating unprecedented opportunities to set foundations of new integrative theories.

    On this front, I have been developing an integrated Eco-Evolutionary framework of Extinction Therapy relevant to the eradication of different types of Metastatic Cancer, and a general framework of Multi-strain Pathogens that addresses challenges of control and elimination from the lense of intra- and inter-specific parasite diversity.

    The study of multi-scale systems often necessitates consideration of structure on different levels, such as demographic heterogeneity in local populations coupled with metapopulation connectivity patterns on broader regional scales, as well as how different forms of structure dynamically evolve and/or emerge over time, as a consequence of within level processes and between level feedbacks.

    My broad interdisciplinary background provides me with appropriate tools for incorporating top-down and bottom-up views in my investigations and also tends to shape the scientific questions I choose to pursue. For example, my approach often includes a combination of Mathematical Models and Computational Agent-Based Stochastic Simulations to represent different levels of system organization, as well as tools from Network Theory and Nonlinear Dynamics, while my questions often relate to unsoled queries in the universe of Complex Systems

     

    Teaching

    • Complexity and Simplicity: Science in the 21st century 
    • Modeling and Simulation
    • The Empirical Cycle
    • Dynamical Systems: Epidemiology of infectious diseases
    • Spatial Processes in Ecology and Evolution: Spatial networks

    Students and Postdocs

    Dr. Martina Ferraguti (PostDoc). Project description: Zoonotic Spillover and its dependency on combined multiple-host and multiple-vector dynamics, as part of the Marie Curie fellowship (will be hosted for 3 months by Prof. Andy Dobson at Princeton U)

    Dr. Christoph Becker (PostDoc). Project description: Energy Transition, as part of the Future of Energy initiative led by the UvA Institute for Advanced Study (co-supervisor: Dr.Vitor Jvasconcelos)

    Sofie te Wierik (PhD candidate). Project description: Governance of Green and Atmospheric water (co-supervisors: Prof. Joyeeta Gupta and Dr. Erik Cammeraat)

    Claudia Meyer (PhD candidate). Project description: A theoretical and experimental study of multiple-virus and multiple-plankton dynamics  (co-supervisors: Prof. Jeff Huisman and Prof. Corina Brussaard)

  • Publications

    2024

    • Meyer, C., Jackson, V. L. N., Harrison, K., Fouskari, I., Bolhuis, H., Artzy-Randrup, Y. A., Huisman, J., Monier, A., & Brussaard, C. P. D. (2024). Temperature modulates dominance of a superinfecting Arctic virus in its unicellular algal host. The ISME Journal, 18(1). https://doi.org/10.1093/ismejo/wrae161
    • Te Wierik, S. A., Keune, J., Miralles, D. G., Gupta, J., Artzy-Randrup, Y. A., Cammeraat, L. H., & van Loon, E. E. (2024). Critical Importance of Tree and Non-Tree Vegetation for African Precipitation. Geophysical Research Letters, 51(20), e2023GL103274. https://doi.org/10.1029/2023GL103274

    2023

    • Ferraguti, M., Dimas Martins, A., & Artzy-Randrup, Y. (2023). Quantifying the invasion risk of West Nile virus: Insights from a multi-vector and multi-host SEIR model. One Health, 17, Article 100638. https://doi.org/10.1016/j.onehlt.2023.100638
    • Freischel, A. R., Teer, J. K., Luddy, K., Cunningham, J., Artzy-Randrup, Y., Epstein, T., Tsai, K. Y., Berglund, A., Cleveland, J. L., Gillies, R. J., Brown, J. S., & Gatenby, R. A. (2023). Evolutionary Analysis of TCGA Data Using Over- and Under- Mutated Genes Identify Key Molecular Pathways and Cellular Functions in Lung Cancer Subtypes. Cancers, 15(1), Article 18. https://doi.org/10.3390/cancers15010018
    • He, D., Lin, L., Artzy-Randrup, Y., Demirhan, H., Cowling, B. J., & Stone, L. (2023). Resolving the enigma of Iquitos and Manaus: A modeling analysis of multiple COVID-19 epidemic waves in two Amazonian cities. Proceedings of the National Academy of Sciences of the United States of America, 120(10), Article e2211422120. https://doi.org/10.1073/pnas.2211422120

    2022

    2021

    2020

    2019

    2018

    2017

    • Day, K. P., Artzy-Randrup, Y., Tiedje, K. E., Rougeron, V., Chen, D. S., Rask, T. S., Rorick, M. M., Migot-Nabias, F., Deloron, P., Luty, A. J. F., & Pascual, M. (2017). Evidence of strain structure in Plasmodium falciparum var gene repertoires in children from Gabon, West Africa. Proceedings of the National Academy of Sciences of the United States of America, 114(20), E4103-E4111. https://doi.org/10.1073/pnas.1613018114 [details]

    2015

    2014

    2012

    • Artzy-Randrup, Y., Rorick, M. M., Day, K., Chen, D., Dobson, A. P., & Pascual, M. (2012). Population structuring of multi-copy, antigen-encoding genes in plasmodium falciparum. eLife, 1, Article e00093. https://doi.org/10.7554/eLife.00093

    2010

    • Artzy-Randrup, Y., & Stone, L. (2010). Connectivity, cycles, and persistence thresholds in metapopulation networks. PLoS Computational Biology, 6(8), Article e1000876. https://doi.org/10.1371/journal.pcbi.1000876
    • Artzy-Randrup, Y., Alonso, D., & Pascual, M. (2010). Transmission intensity and drug resistance in malaria population dynamics: Implications for climate change. PLoS ONE, 5(10), Article e13588. https://doi.org/10.1371/journal.pone.0013588
    • Meer, M. V., Kondrashov, A. S., Artzy-Randrup, Y., & Kondrashov, F. A. (2010). Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness. Nature, 464, 279-282. https://doi.org/10.1038/nature08691

    2009

    • Berchenko, Y., Artzy-Randrup, Y., Teicher, M., & Stone, L. (2009). Emergence and size of the giant component in clustered random graphs with a given degree distribution. Physical Review Letters, 102(13), Article 138701. https://doi.org/10.1103/PhysRevLett.102.138701
    • Berchenko, Y., Artzy-Randrup, Y., Teicher, M., & Stone, L. (2009). The big friendly giant: the giant component in clustered random graphs. In Modeling and Simulation in Science, Engineering and Technology (pp. 237-252). (Modeling and Simulation in Science, Engineering and Technology; Vol. 42). Springer Basel AG. https://doi.org/10.1007/978-0-8176-4751-3_14
    • Zvuloni, A., Artzy-Randrup, Y., Stone, L., Kramarsky-Winter, E., Barkan, R., & Loya, Y. (2009). Spatio-temporal transmission patterns of black-band disease in a coral community. PLoS ONE, 4(4), Article e4993. https://doi.org/10.1371/journal.pone.0004993

    2008

    • Dagan, T., Artzy-Randrup, Y., & Martin, W. (2008). Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution. Proceedings of the National Academy of Sciences of the United States of America, 105(29), 10039-10044. https://doi.org/10.1073/pnas.0800679105
    • Zvuloni, A., Artzy-Randrup, Y., Stone, L., van Woesik, R., & Loya, Y. (2008). Ecological size-frequency distributions: How to prevent and correct biases in spatial sampling. Limnology and Oceanography: Methods, 6(3), 144-153. https://doi.org/10.4319/lom.2008.6.144

    2007

    2006

    • Artzy-Randrup, Y., & Kondrashov, A. S. (2006). Sympatric speciation under incompatibility selection. Proceedings of the National Academy of Sciences of the United States of America, 103(31), 11619-11624. https://doi.org/10.1073/pnas.0602339103

    2005

    • Artzy-Randrup, Y., & Stone, L. (2005). Generating uniformly distributed random networks. Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 72(5), Article 056708. https://doi.org/10.1103/PhysRevE.72.056708

    2017

    • Artzy-Randrup, Y. A. (2017). Evidence of strain structure and the theory of malaria control. Abstract from Annual Meeting NVTB 2017, Schoorl, Netherlands.
    • Artzy-Randrup, Y. A. (2017). Exploring the implications of climate change on epidemiological dynamics of multi-host vector-borne diseases. Abstract from PARSA, 3rd International Congress on Parasites of Wildlife, South Africa.

    2016

    • Artzy-Randrup, Y. A. (2016). Inferring transmission mode of white plague-like coral disease from its spatio-temporal pattern. Poster session presented at NAEM, .

    2015

    • Artzy-Randrup, Y. A. (2015). Spatial Modeling of White-Plague Coral Disease. Poster session presented at Epidemics 5, Florida, United States.

    2014

    • Artzy-Randrup, Y. A. (2014). Co-dependence between parasite intra-specie diversity and Long-term persistence. Poster session presented at MBI - Sustainability and Complex Systems , Columbus, OH, United States.
    • Artzy-Randrup, Y. A. (2014). Social relationships and intrinsic attributes in product valuation in cultural markets. Poster session presented at NIMBios - Animal Social Networks , Knoxville, Tennessee, United States.
    • Artzy-Randrup, Y. A. (2014). Synergistic and antagonistic interactions between bed-nets and vaccines in the control of malaria. Poster session presented at The American Society of Tropical Medicine and Hygiene (ASTMH) 63rd Annual Meeting, New Orleans, LA, United States.
    • Artzy-Randrup, Y. A. (2014). Synergistic and antagonistic interactions between bednets and vaccines in the control of malaria. Poster session presented at Challenges in Malaria Research: Core science and innovation conference, Oxford, United Kingdom.
    • Artzy-Randrup, Y. A. (2014). Synergistic and antagonistic interactions in malaria control. Poster session presented at Challenges in Malaria Research: Core science and innovation conference, Oxford, United Kingdom.

    2013

    • Artzy-Randrup, Y. A. (2013). Parasite Diversity: Implications for Disease Control. Poster session presented at 4th International Conference on Infectious Disease Dynamics, Amsterdam, Netherlands.

    Media appearance

    Journal editor

    • Artzy-Randrup, Y. (editor) (2020-2030). Biological Invasions (Journal).

    Others

    • Artzy-Randrup, Y. (participant) (12-1-2018). Programme in silico based science meeting, Amsterdam (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (19-9-2016 - 22-9-2016). Conference on Complex Systems 2016, Amsterdam (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (8-12-2014 - 12-12-2014). Lorentz Workshop Spatio-temporal Dynamics in Ecology: Building Bridges between Ecology and the Mathematical and Physical Sciences, Leiden, The Netherlands. Spatio-Temporal Dynamics in Ecology (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (8-12-2014 - 12-12-2014). Lorentz Workshop Spatio-temporal Dynamics in Ecology: Building Bridges between Ecology and the Mathematical and Physical Sciences, Leiden, The Netherlands (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (2-11-2014 - 6-11-2014). The American Society of Tropical Medicine and Hygiene (ASTMH) 63rd Annual Meeting, New Orleans, LA (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (22-5-2014 - 23-5-2014). NVTB meeting, Schoorl (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (6-3-2014 - 8-3-2014). NIMBios - Animal Social Networks, Knoxville, Tennessee (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (11-2-2014 - 12-2-2014). NAEM congress, Lunteren (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (19-11-2013 - 22-11-2013). Epidemics 4, Amsterdam (participating in a conference, workshop, ...).
    • Artzy-Randrup, Y. (participant) (16-9-2013 - 20-9-2013). MBI - Sustainability and Complex Systems, Columbus, OH (participating in a conference, workshop, ...).

    2024

    2024

    • Bolhuis, H., Huisman, J., Brussaard, C. P. D., Artzy-Randrup, Y. A., Meyer, C., Jackson, V. E. & Monier, A. (2024). Dataset Meyer et al. Rising temperature modulates dominance of a superinfecting virus in its unicellular Arctic algal host - FCM and qPCR, Supplement figures. NIOZ. https://doi.org/10.25850/nioz/7b.b.ch
    This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list.
  • Ancillary activities
    • No ancillary activities