DIEP seminar by Andrea Luppi
Modelling how brain function emerges from network architecture in space and time
Disentangling how cognitive functions emerge from the interplay of brain dynamics and network architecture is among the major challenges faced by neuroscientists. Addressing these complex challenges requires a concerted integration of theory and data. In this talk, I will show how we can investigate the spatial and temporal dimensions of structure-function relationships in the brain, by combining the formal tools of network science with pharmacological and pathological perturbations.
I will show how perturbations of consciousness induce convergent reconfigurations of the brain’s unimodal-transmodal functional architecture. However, loss of consciousness increases structural constraints on brain dynamics across scales, whereas psychedelics decouple brain function from anatomy. Computational models provide a formal way to integrate our understanding.
If you wish to attend this seminar online, please send an email to f.a.nobregasantos@uva.nl to receive the zoom-link.