We live in a fast-changing world where everything seems to be interwoven with everything else. At the IAS, researchers from a wide range of fields work together on all kinds of complex scientific and societal challenges. We have organised our activities into three broadly defined domains, under which you can find a colourful array of projects and theme groups. The projects and themes change over time, but our foundations and methods programme remains. It is the core of the institute. This programme focuses on advancing fundamental research in an interdisciplinary context, and on developing novel integrative methodology for the big challenges we face in science and society. By studying and discussing the fundamental concepts of complexity (e.g. causality, emergence, resilience) that are found in many of today’s most pressing challenges, and by developing new integrative approaches and tools (e.g. computational and descriptive methods) we aim to bridge disciplines, scales and paradigms and unravel wicked problems.